Cosmetic Ingredients
Fisetin Powder
Fisetin Powder, a natural flavonoid compound and one of Kintainutri®'s core plant extracts, is primarily derived from the natural plant of Cotinus coggygria, a member of the Anacardiaceae family, and is produced through advanced extraction and purification processes. This product is a light yellow to yellow fine powder, odorless, and well-soluble. Standard supply specifications contain ≥98% fisetin purity (HPLC assay), and various purity grades can be customized upon request. It exhibits excellent antioxidant properties, helping to scavenge free radicals.
As a popular anti-aging ingredient, it excels in supporting healthy aging and maintaining cell vitality. It has a wide range of applications, including dietary supplements (such as capsules and tablets), functional foods, and cosmetic ingredients. As a professional plant extract powder supplier with years of experience in the industry, Kintainutri® consistently adheres to product standards of "naturalness, high purity, and stability." From raw material selection to production quality control, strict GMP regulations are adhered to ensure that every batch of Fisetin Powder meets international quality standards, providing reliable raw material support to global customers.
As a popular anti-aging ingredient, it excels in supporting healthy aging and maintaining cell vitality. It has a wide range of applications, including dietary supplements (such as capsules and tablets), functional foods, and cosmetic ingredients. As a professional plant extract powder supplier with years of experience in the industry, Kintainutri® consistently adheres to product standards of "naturalness, high purity, and stability." From raw material selection to production quality control, strict GMP regulations are adhered to ensure that every batch of Fisetin Powder meets international quality standards, providing reliable raw material support to global customers.
Contact us Fisetin Powder Production Process
Kintainutri®'s Fisetin Powder production adheres to a rigorous, standardized, full-process system encompassing "raw material traceability - meticulous extraction - purification and refinement - quality control and packaging" to ensure product purity and safety. The specific steps are as follows:
Raw Material Screening and Pretreatment: Leaves or bark from high-quality plants, such as Cotinus coggygria and Acacia chinensis, are carefully selected and sorted to remove impurities. The leaves and bark are then cleaned, low-temperature dried (≤60°C to preserve the active ingredients), and crushed to a fineness of 80-100 mesh in preparation for subsequent extraction.
Raw Material Screening and Pretreatment: Leaves or bark from high-quality plants, such as Cotinus coggygria and Acacia chinensis, are carefully selected and sorted to remove impurities. The leaves and bark are then cleaned, low-temperature dried (≤60°C to preserve the active ingredients), and crushed to a fineness of 80-100 mesh in preparation for subsequent extraction.
Efficient Extraction: An ethanol-water solution (food-grade ethanol, with the concentration adjusted based on the raw material characteristics) is used as the extraction solvent. A dynamic reflux extraction process (extraction temperature 55-65°C, extraction time 2-3 hours) is used to fully dissolve the Fisetin component from the raw materials and minimize the release of ineffective impurities.
Filtration and Concentration: The extract is first filtered through a plate and frame filter to remove solid impurities such as crude fiber, and then concentrated under reduced pressure (vacuum concentration < 100°C). The ethanol solvent is recovered (recovery rate ≥95%, meeting environmental protection requirements) at a pressure of 0.08-0.09 MPa and a temperature of ≤50°C) to obtain a crude Fisetin extract.
Purification Process: The crude extract is dissolved in purified water and then separated using macroporous resin adsorption separation technology to precisely adsorb the active ingredient Fisetin. This is then purified using a gradient elution solution to remove flavonoid impurities. The eluate is further concentrated under reduced pressure and spray-dried at low temperature (inlet air temperature 180-200°C, outlet air temperature 80-90°C) to obtain the Fisetin primary powder.
Fine Grinding and Quality Control: The primary powder is ultrafinely ground to a 200-mesh fineness to ensure powder uniformity and solubility. Purity is then tested by HPLC (requires ≥98%). Heavy metal (lead, mercury, arsenic, etc.) and microbial (colony count, mold, etc.) testing is also performed to ensure compliance with international safety standards.
Sterile Packaging: Qualified Fisetin powder is packaged in a Class 10,000 cleanroom in aluminum foil vacuum bags or pharmaceutical-grade sterile packaging. Packed in HDPE barrels, each labeled with batch, production date, and purity information, it undergoes metal detector inspection to prevent foreign matter and ensure product stability during storage and transportation.
The entire production process strictly adheres to GMP standards, with real-time monitoring at key stages. Through process optimization and quality control upgrades, Kintainutri® improves the extraction rate of Fisetin while maximizing its biological activity, providing customers with a high-purity, highly stable raw material product.
Fisetin Powder Specification
| Product name |
Fisetin Powder |
|---|---|
| Extract source | Dew grass |
| Extraction Solvent | Water/Ethyl alcohol |
| Appearance | Yellow powder |
| Solubility | Soluble in ethanol, slightly soluble in acetone, slightly soluble in ethyl acetate, chloroform and hot water, almost insoluble in ether |
| Identification | TLC , HPLC |
| Sulphated Ash | NMT 0.5% |
| Heavy metals | NMT 20 PPM |
| Loss On Drying | NMT 5.0% |
| Powder size | 80Mesh, NLT90% |
| Assay of Ecdysterone (HPLC test, percent, Standard in House) | Min. 98.0% |
| Microbiological Quality (Total viable aerobic count) | |
| - Bacteria, CFU/g, not more than | NMT 10³ |
| - Moulds and yeasts, CFU/g, not more than | NMT 10² |
| - E.coli, Salmonella, S. aureus, CFU/g | Absence |
| Shelf life | 2 years if sealed and store away from direct sun light. |
Fisetin Powder Application
Due to the natural activity and high purity of Fisetin Powder, Kintainutri® products are widely applicable in various healthcare industry scenarios, meeting the raw material needs of diverse customers. Its core application areas are as follows:
Dietary Supplements: As a popular anti-aging and antioxidant ingredient, Fisetin can be directly used in the production of dietary supplements such as capsules, tablets, and powders. Common dosages contain 100-500mg of Fisetin per dose, helping consumers maintain cell vitality and support healthy aging through daily supplementation. The powder's high solubility allows for easy combination with ingredients such as vitamin E and coenzyme Q10 to enhance the product's overall efficacy.
Functional Foods: Fisetin can be added to foods such as breakfast cereals, protein powders, solid beverages, and compressed candies. For example, adding 0.5%-1% Fisetin to functional cereals specifically formulated for middle-aged and elderly individuals does not affect the original taste of the food while providing the product with antioxidant and light health benefits. Its properties align with current healthy eating trends.
Cosmetics: With its excellent antioxidant capacity, it can be added as an active ingredient in skincare products such as anti-wrinkle creams, serums, and eye creams. Typical addition levels are 0.1%-0.5%. It helps scavenge free radicals and slow collagen loss. When combined with ingredients like hyaluronic acid and vitamin C, it enhances skin moisturizing and anti-aging effects. Its high purity and impurity-free nature reduce the risk of skin allergies.
Research and Pharmaceutical Intermediates: High-purity (≥98%) Fisetin can be used as an experimental raw material by research institutions and pharmaceutical companies for applications such as aging mechanism research and drug development. Kintainutri® offers customized purity (up to 99.5%) and small-batch packaging to meet the precise needs of research experiments.
Pet Health: With the rise of the pet health market, Fisetinis becoming increasingly popular. It is also used in pet dietary supplements (such as pet health capsules and nutritional creams) to help middle-aged and elderly pets maintain joint health and boost immunity. Because it's natural and non-irritating, and suitable for pets with sensitive constitutions, it's favored by pet product companies.
Kintainutri® offers customized powder fineness (80-200 mesh available), packaging specifications (1kg/bag to 25kg/drum), and relevant certification documents (COA, MSDS, etc.) to meet the needs of different application scenarios, helping customers efficiently develop end products.
Fisetin Powder Dosage
Application Field |
Recommended Addition Level |
Typical End-Product Form |
Dietary Supplements |
100 - 500 mg per serving |
Capsules, Tablets, Powder Blends |
Functional Foods |
0.5% - 1% of total formula |
Breakfast Cereals, Protein Powders, Solid Drinks |
Note: The above dosages are for reference only. Kintainutri® recommends adjusting based on specific product formulas, regional regulatory requirements, and target efficacy.
Why Choose Kintainutri® Fisetin Powder?
As a professional supplier of plant extracts, Kintainutri®'s Fisetin offers reliable quality and service to downstream manufacturers. Key reasons for choosing Kintainutri® are:
Strict quality control and stable purity: Raw materials are sourced from compliant plantations with full traceability. HPLC is used throughout the production process to ensure Fisetin's purity remains stable at ≥98%. Heavy metal (lead, mercury, etc.) and microbiological indicators are significantly below international standards. Each batch of product is accompanied by a complete Certificate of Analysis (COA), ensuring reliable use in production without the need for additional testing.
Flexible customization to meet diverse needs: Powder fineness (80-200 mesh) and packaging specifications (from 1kg bags to 25kg drums) can be customized based on the characteristics of the customer's end product. Small batches as small as 100g are also available for trial use, helping customers reduce R&D and pilot production costs and rapidly accelerate product launch. Efficient Response, Full-Life Service: Dedicated account managers respond to inquiries and orders within 24 hours. We provide MSDS, FDA filings, and other certification documents to assist customers with market regulation and compliance audits. We partner with renowned international freight forwarders for logistics, ensuring timely and safe product delivery.
Cost Advantages, Outstanding Value: Through large-scale raw material procurement and optimized extraction processes (ethanol recovery rate ≥ 95%), we reduce production costs while ensuring quality. We provide customers with competitive quotes and help them increase their end-product profit margins.
Strict quality control and stable purity: Raw materials are sourced from compliant plantations with full traceability. HPLC is used throughout the production process to ensure Fisetin's purity remains stable at ≥98%. Heavy metal (lead, mercury, etc.) and microbiological indicators are significantly below international standards. Each batch of product is accompanied by a complete Certificate of Analysis (COA), ensuring reliable use in production without the need for additional testing.
Flexible customization to meet diverse needs: Powder fineness (80-200 mesh) and packaging specifications (from 1kg bags to 25kg drums) can be customized based on the characteristics of the customer's end product. Small batches as small as 100g are also available for trial use, helping customers reduce R&D and pilot production costs and rapidly accelerate product launch. Efficient Response, Full-Life Service: Dedicated account managers respond to inquiries and orders within 24 hours. We provide MSDS, FDA filings, and other certification documents to assist customers with market regulation and compliance audits. We partner with renowned international freight forwarders for logistics, ensuring timely and safe product delivery.
Cost Advantages, Outstanding Value: Through large-scale raw material procurement and optimized extraction processes (ethanol recovery rate ≥ 95%), we reduce production costs while ensuring quality. We provide customers with competitive quotes and help them increase their end-product profit margins.
Place your order now and experience the unique charm of Kintainutri®!
Shipping & Packaging
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● Packaging: Inside food grade bag, outer aluminum foil bag.25kg use double-layer plastic container/fiber drum.Or your choice.● OEM Service Available: Customized packaging available, click here to know more.● Shipping: DHL / FEDEX / EMS/ BY AIR / BY SEA● American Warehouse: KINTAI put over 100 natural plant extract ingredients in our US warehouse for fast delivery.● Payment: We accept payment by T/T, L/C, Paypal, and Wester Union.Please contact us and we will guide you with an easy and professional way for your order.
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